What it is
MOTS-c is encoded by mitochondrial DNA rather than nuclear DNA, which makes it part of a small and unusual family of 'mitochondrial-derived peptides'.
How it's described to work
Research associates MOTS-c with AMPK signaling — a central regulator of cellular energy — and it is often described in the literature as an exercise-mimetic under investigation.
What research discusses it for
Metabolic researchExercise physiologyCellular energy research
Important context
Early-stage science. Educational content only.